XXY persons are male. They are not a separate or new sex. Chromosome anomalies are quite rare, but real. They don't result in any new sexes. CAIS is also very rare, but CAIS persons are typically XY males with a defective SRY gene. They look female, but never have any children. I would say, they are outside of the male/female binary. I should add, that they view themselves as female (which they are not), and (in my opinion) should be treated as females, with the possible exception of sports.