Some medical decisions are easy. If you have hypothyroidism, take levothyroxine for the rest of your life. If you are going blind, get cataract surgery. Some medical decisions are more difficult, but we do have treatment histories. If you need a kidney transplant, go ahead if you can get a kidney with the understanding that you will be on anti-rejection drugs for the rest of your life and, therefore, immunocompromised. If you have stage 4 cancer, consider treatment versus quality of the rest of your life. Some medical decisions should be made only after careful consideration of at least all known risks and benefits. I suspect gender affirming therapy for children should be one of those decisions.
However, all medical decisions are made more difficult because the public does not understand that there are risks and benefits to taking any medication and/or having any medical procedure.