The film and TV blacklists of the 50' and 60's. The Smothers Brothers cancelled for making fun of the President in 1969. Bill Maher's show "Politically Incorrect" in 2001 for not backing the Bush WH spin on 9/11. "Ellen" dropped by advertisers under pressure from anti-LGBTQ organizations. Kathy Griffin 2017 for a picture SHE never released to the public. The major difference today is the plus factor of the antisocial media platforms which have empowered the forces hostile to free speech with outsize influence. If you stand outside of the social media battlefield you won't know who is being cancelled at all. As long as there is public opinion there will be some form of cancel culture--- right now the Yale Business School is trying to cancel businesses that can't or won't disengage from Russia. The Bulwark supports that kind of cancel culture. In the Amazon series "Upload" the evil corporation gives their staff coffee mugs that say "Don't Be Evil. Obviously". That is the warning that cancel culture really sends.