When I was talking with a research doctor about GLP-1s, he highlighted how many neurons we have in the stomach and intestine to begin with (I believe this is the enteric nervous system?) and that the "brain drug" effects may be more distributed than just the literal brain. Is that consistent with the effects you were describing here?

It made me wonder if that is a common root cause of all these other symptoms, that essentially something in modern life is pressing on the ENS and it's creating these diverse symptoms. So when that pressure is relieved, a bunch of seemingly unconnected symptoms resolve. It doesn't really fit with GLP-1s binding throughout the body, which strikes me as the most obvious candidate, but I hadn't seen anyone else highlight it as plausible pathway.