Well, it's a pooled human blood product. That's kind of creepy for one, but for two, there's a great deal of different proteins present in it, which seems like a bad idea if you're concerned with possible reactions. Much cleaner to get the toxoid injection (?).

Here's the prescriber info for HyperTet (tetanus immune globulin): hypertet.com/documents/…

Check the warnings. The manufacturer doesn't allow copy/paste from the document, interestingly.