What we can observe from the data is that cancer and heart/vascular disease related deaths increased significantly in 2020-21. But the slope began to increase before vaccines were available. Several physicians I know have commented that the COVID extremes resulted in diversion of resources and deferred treatment for other conditions. One speculated that the dramatic decrease in screening resulting from mandates is a logical explanation for greater severity of outcomes (in plain language: more deaths because we're not finding it early enough to do anything useful). A consequence of poor risk management IMO.

For myself I can say my physical condition was adversely affected when the forced closure of gyms, bars and nightclubs. Between the three that's where I get most of my exercise ;-).