In Nebraska, fish are exposed to herbicides in agricultural runoff. The study objectives were to determine 1) if fathead minnows and northern leopard frogs exposed to atrazine experience alterations in gene expression, and 2) whether these changes are elicited by a simulated herbicide mixture. Following a 7-d exposure to atrazine, female minnows were defeminized, whereas male frogs were feminized. The mixture did not elicit statistically significant effects in either species. Environ Toxicol Chem 2018;37:1182-1188. © 2018 SETAC.
Keywords: Aquatic toxicology; Endocrine disruptor; Herbicide; Mixture; Pimephales promelas; Rana pipiens.
© 2018 SETAC.