I am so glad I found your newsletter! I truly believe that we must question with frequency, although this can lead me to uncertainty fatigue. My brain has a way of going on pause to rest and recover (sometimes too long). Evidence Based Medicine is an approach to practicing medicine that encourages questioning, searching for evidence (in the scientific literature) to answer the question, critiquing what evidence is found and the applying the answers (which all come with varying strength) to a patient's predicament (medical issue). Essentially translating a scientific discover to a real-time personal dilemma. Some physicians do not accept EBM because it challenges the "art" of medicine (aka, their chosen dogma). I think the beauty and positive impact of EBM, like science, is to strive toward the most scientifically valid answers not THE answer, as that is not 100% achievable. Maybe there are little lightning bolts and bigger ones?