Thanks Shanaka, fascinating information!

“Lifespan extension and rejuvenation are not the same achievement” made me recall :

“In Greek mythology, immortality without youth is famously exemplified by the tragic story of Tithonus. A Trojan prince and lover to Eos, the goddess of the dawn, he was granted eternal life by Zeus at her request, but she forgot to ask for eternal youth as well.

Consequently, Tithonus aged continuously, becoming increasingly frail, withered, and senile. Trapped in an endless state of decay, unable to die.”