Li et al. (2018) and Hornung et al (2008) concluded that Aluminum adjuvants in vaccines can activate inflammasome pathways in Natural Killer cells and dendritic cells. Those two immune cells are critical in maintaining homeostasis by using apoptotic signaling to take out infected cells in a non-inflammatory way. When inflammasome pathways are activated, the cells secrete highly inflammatory cytokines that can be very destructive to neuronal tissues leading to symptoms of autism and Alzheimer's.