Yes, traditional vaccines are different both in the way they work and in their generally expected sterilising effect. As I understand it, an interesting exception is polio: one type is sterilising and the other type is not but has low side-effect rates. This is why, until the 90s, the U.S. had a regimen of administering both oral and injectable polio vaccines, in order to minimise side-effects while avoiding the systemic risk of non-sterilising vaccines.