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In today’s newsletter, I cover a study that’s already in the running for “coolest scientific finding of the year.”

It finds that the brain—specifically a set of neurons in the ventromedial hypothalamus (VMH)—is a key intermediate for improvements in endurance capacity.

1. Exercise strengthens inputs to and increases the activity of these SF1 neurons in the VMH.

2. Activation of SF1 neurons following exercise is required to improve endurance.

3. Exogenous activation of SF1 neurons following exercise enhances endurance gains (while inhibition of them diminishes adaptations).

bradyholmer.substack.co…

Physiology Friday #306: How Exercise Hardwires the Brain for Endurance
Feb 20
at
4:55 PM
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