You can't sell turkey tail mushrooms, a 2000 year old adaptogenic superfood because it's ânovelâ, and yet these clowns were able to inject an agent in billions of arms without knowing how it works.
â⌠They are only metastable and bind seemingly randomly to endogenous proteins almost immediately. As of the time of this lecture, this process is still not sufficiently understood.â
â⌠There is not much to say about the biodegradation of the individual lipids, not because there is little to say, but because these processes are poorly understood. Very few studies have been conducted, and current knowledge of the precise degradation pathways remains largely speculative.â
â⌠Furthermore, it appears biologically plausible that DSPCsâthat is, the synthetic phospholipids of LNPsâmay, even after degradation, be recycled and reintegrated into the cell membrane, thereby altering the overall membrane structure. In other words: we know almost nothing about the long-term consequences.â