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Stopping anticoagulants after successful Afib ablation.

I loved this study!

If you’ve had an ablation for atrial fibrillation and were told your rhythm is “fixed,” can you stop anticoagulation?

A study looked at this exact question. I have no affiliation to this article or study - I'm a private practice physician and just sharing the importance of this study for my own patients and perhaps yourself.

ALONE-AF was a randomized trial in patients who had no documented atrial arrhythmia recurrence for at least 12 months after AF ablation and had at least 1 non–sex-related stroke risk factor.

They compared discontinuing OAC vs continuing OAC and found:

  • Primary composite outcome (stroke, systemic embolism, or major bleeding) was lower with discontinuation: 0.3% vs 2.2%, mainly because there were fewer major bleeding events in the discontinuation group.

  • Ischemic events were rare in both groups, and differences in stroke/systemic embolism were not statistically significant in the trial reporting.

Top 3 questions I'd want my patients to ask me:

  1. “Am I truly low enough risk to consider stopping my blood thinner?”

  2. “How certain are we that my AFib has not come back?”

  3. “What is my bleeding risk if I stay on anticoagulation?”

jamanetwork.com/journal…

Feb 27
at
8:31 PM
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