No — chromium and cromolyn are completely different, and the confusion is very common because the names sound similar.

Chromium is a trace mineral (often taken as chromium picolinate) involved in glucose and insulin metabolism and is sometimes used for blood sugar support. Cromolyn (cromolyn sodium) is a prescription medication that stabilizes mast cells and helps prevent the release of histamine and other inflammatory mediators; it’s commonly used in conditions like asthma and mast cell activation syndrome (MCAS). Chromium does not stabilize mast cells, and cromolyn does not act as a mineral or affect blood sugar. Despite the similar-sounding names, they are unrelated in function, use, and mechanism — and they are not interchangeable.