Timon: nice pushback on the INTERHEART findings: a handful of factors explain most heart attack risk, but these factors are hard to change. Quitting smoking is almost impossible difficult. Fair. Hard to change behavior and hard to modify risk are not equal statements. Smoking is a behavioral mountain climb. Blood pressure and cholesterol are two of the most treatable conditions in all of medicine. Most of the risk doesn’t sit in thr impossible bucket. It sits in the solvable one we routinely undertreat.