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It is my understanding that they used the pseudouridine because it:

“It is demonstrated that Ψ can enhance RNA stability and, in the meantime, decrease anti-RNA immune response (Karikó et al., 2008)”

Beyond this, are there studies that show the safety of using pseudouridine long them. I didn’t see any.

The Critical Contribution of Pseudouridine to mRNA COVID-19 Vaccines

frontiersin.org/article…

Apr 9, 2023
at
11:55 PM

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