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Have tried many many substances though only pharmaceutical versions of opiates and methamphetamines which are low dose compared to recreational use. Deep first jhana is much more like a full body orgasm that lasts for anywhere from a few minutes to a few hours (I have personally experienced up to 10-15 minutes, hard to judge time, didn't have a clock at the time, can only enter them on demand on retreat.) This is much more pleasureable than drugs on the pure physical pleasure and contentment axes, though psychedelics + mdma can lead to insights that are a different axis of pleasure/happiness. I imagine that high dose opiates hit many of the same dimensions of first jhana, but with the problem of dullness that scales with dose, whereas jhana is vivid.

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