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I'm late commenting but I don't see anyone mentioning metformin yet.

** THIS IS NOT MEDICAL ADVICE **

Metformin is off-patent and although its only on-label use is for diabetes, some people think it extends life expectancy. (The main evidence for this is that diabetics who take metformin live longer on average than people who aren't diabetic.)

Since I started taking it my blood sugar has dropped from the high end of the normal range to the low end, which I imagine is a good place for it to be. And I've lost a noticeable thought not dramatic amount of weight: maybe 5% or thereabouts, which moved me from "overweight" to the high end of normal.

Surely people who are thinking about taking semaglutide should try metformin first?

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